Kamis, 30 Juni 2011

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  • Published on: 1800
  • Binding: Paperback

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Senin, 27 Juni 2011

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In recent years, research has shown the importance of peptides in neuroscience, immunology, and cell biology. Active research programs worldwide are now engaged in developing peptide-based drugs and vaccines using modification of natural peptides and proteins, design of artificial peptides and peptide mimetics, and screening of peptide and phage libraries.
In this comprehensive book, the authors discuss peptide synthesis and application within the context of their increasing importance to the pharmaceutical industry. Peptides: Synthesis, Structures, and Applications explores the broad growth of information in modern peptide synthetic methods and the structure-activity relationships of synthetic polypeptides.

Coverage includes:
* The history of peptide chemistry
* Amide formation, deprotection, and disulfide formation in peptide synthesis
* Solid-phase peptide synthesis
* a-helix formation by peptides in water
* Stability and dynamics of peptide conformation
* An overview of structure-function studies of peptide hormones
* Neuropeptides:peptide and nonpeptide analogs
* Reversible inhibitors of serine proteinases
* Design of polypeptides
* Current capabilities and future possibilities of soluble chemical combinatorial libraries
* Epitope mapping with peptides
* Synthesis and applications of branched peptides in immunological methods and vaccines

  • Sales Rank: #4541567 in Books
  • Published on: 1995-11-02
  • Original language: English
  • Number of items: 1
  • Dimensions: 9.33" h x 1.24" w x 6.30" l, 1.94 pounds
  • Binding: Hardcover
  • 511 pages

From the Back Cover
In recent years, research has shown the importance of peptides in neuroscience, immunology, and cell biology. Active research programs worldwide are now engaged in developing peptide-based drugs and vaccines using modification of natural peptides and proteins, design of artificial peptides and peptide mimetics, and screening of peptide and phage libraries.
In this comprehensive book, the authors discuss peptide synthesis and application within the context of their increasing importance to the pharmaceutical industry. Peptides: Synthesis, Structures, and Applications explores the broad growth of information in modern peptide synthetic methods and the structure-activity relationships of synthetic polypeptides.
Coverage includes:
* The history of peptide chemistry
* Amide formation, deprotection, and disulfide formation in peptide synthesis
* Solid-phase peptide synthesis
* a-helix formation by peptides in water
* Stability and dynamics of peptide conformation
* An overview of structure-function studies of peptide hormones
* Neuropeptides:peptide and nonpeptide analogs
* Reversible inhibitors of serine proteinases
* Design of polypeptides
* Current capabilities and future possibilities of soluble chemical combinatorial libraries
* Epitope mapping with peptides
* Synthesis and applications of branched peptides in immunological methods and vaccines

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Peptide Perfect
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Exactly what I wanted. Delivered in perfect condition. Research level reference book!!!

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  • Published on: 2004-12-17
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Le code du dragon: «Que cachent les souterrains de l'antique Collège de Raxford? Et qui a enlevé Hans Ratello? Pour résoudre cette énigme, il faut un groupe de filles vraiment spéciales: les Téa Sisters! Voici l'histoire de leur première et fantastique aventure...»

  • Sales Rank: #3178888 in Books
  • Published on: 2006-05-01
  • Original language: French
  • Number of items: 1
  • Dimensions: .90" h x 5.60" w x 8.30" l, .80 pounds
  • Binding: Paperback

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  • Sales Rank: #1739231 in Books
  • Published on: 2009-05-12
  • Released on: 2009-05-12
  • Original language: English
  • Number of items: 1
  • Dimensions: 9.08" h x .66" w x 6.77" l, 1.14 pounds
  • Binding: Paperback
  • 192 pages

Review
"Design your life is an utter pleasure, like a delicious tray of warm brownies that also happen to be nutritious. I've never encountered a book about design so smart and fun and unpretentious and easy to love." - Kurt Andersen, author of Heyday And Turn Of The Century."

About the Author
ELLEN LUPTON is curator of contemporary design at the Cooper- Hewitt Museum and director of the MFA program at Maryland Institute College of Art. She is the author of Thinking with Type and D.I.Y.: Design It Yourself.
JULIA LUPTON teaches at the University of California, Irvine and is co-chair of the Design Alliance. She is the author of several books on Shakespeare and co-authored D.I.Y. Kids with her sister Ellen.

Excerpt. © Reprinted by permission. All rights reserved.
Design Your Life
HERE AND THEREMOVING THE FURNITUREI found myself in a narrow room. Two vinyl-covered armchairs faced the foot of my bed; a small steel table on wheels was stationed in a far corner. Was it a minimum security prison for inside traders? No, it was the hospital room where I was sent to rest after delivering my second baby. Holding my newborn daughter against my chest and grateful for the basic comforts of this ordinary room, I didn't give a second thought to how it was designed.My husband Abbott, however, paced around the room, seeing flaws in its arrangement and seeking ways to improve it. He brings this creative and critical eye everywhere he goes. At his sister's house one holiday, he reshuffled the light bulbs in the living room, changing the wattage in each lamp to make the setting more sociable--brighter here, dimmer there. Invited to lecture at a university, he realigned a rigid battalion of chairs into relaxed, staggered waves.Here in this hospital room, our son would meet his baby sister for the first time, and my parents would hold their newest granddaughter. The poorly sited armchairs would have placed our guests at the end of my weary body, so Abbott moved them near the window and alongside the bed. He commandeered an extra chair from the hallway and added it to this newly assembled seating area. The steel table migrated there as well, providing a resting spot for cups of coffee and cans of Coke as well as a vase of flowers.As I cradled our sleeping daughter in my arms, I watched an indifferently planned space become a room that welcomed visitors and encouraged lingering and conversation.Ten years later, the kids and I have learned a lot from Abbott's penchant for moving furniture. Although we are sometimes mystified by his constant attention to how things are arranged, in the end, he nearly always succeeds in making the spaces we live in brighter, or more comfortable, or simply refreshed and renewed. Change, in itself, keeps our rooms alive."Daddy is a poltergeist," I say to our kids, explaining how massive pieces of furniture have managed to move from room to room while we were out playing at the park."Daddy has a furniture problem," I declare, as Abbott enters the house one Sunday heaving along two vintage Florence Knoll end tables and a George Nelson desk purchased from a local antique dealer."They had just arrived in the store when I got there," he exclaims, glowing with exertion and delight."How much?""Not cheap.""Where will they go?""I'll find a place."A clunky ballet ensues as tables, chairs, and sofas seek alternate lodging throughout the house, where they enjoy new lives in new locations. Many people avoid moving furniture, putting in place their couch, chairs, coffee table, and lamps, and leaving them there for years, even a lifetime. The furniture melts into the floor and becomes invisible. My maternal grandmother lived in several different homes when I was growing up, and she managed to arrange the furniture the same way wherever she went. It was as if she hadn't moved at all.In the Middle Ages and Renaissance, domestic spaces were reconfigured daily, with one large room accommodating work, meals, and sleep. The French word for "furniture" is meubles, meaning "moveable"; Spanish is muebles, Italian is mobili, and Portuguese is mobiliário. Chairs are the ultimate moveable furnishings, easily reconfigured to create circles of conversation or rows of attention. Portable folding chairs date from antiquity.In our era of more frozen floor plans, rezoning often occurs as families expand and contract--adding new members, adapting to changing abilities and disabilities, expelling grown children and absorbing aging parents. But furniture needn't wait for major life changes in order to be moved. When we recently shifted a marble coffee table from one sitting area to another, we discovered that the piece reflects more light in its new setting, subtly changing the entire room.People who never move their furniture stop seeing their environment. They get used to banging into an awkwardly placed bureau, bruising their shins on it over and over without deciding to shift its position. They avoid sitting in an uncomfortable chair, but don't replace it, and they stop using a drawer that sticks, but don't fix it. A vase or curio waits unnoticed in its cabinet, and works of art fade away into the paint and plaster.A few years ago, our Baltimore town house became a location for a Hollywood film. Over the course of a week, we saw our rooms transformed not just once but several times. The set decorator, a big bossy blonde from Los Angeles, borrowed chairs, tables, sofas, and beds from furniture stores around the city; most pieces were sent back in failure as she searched for just the right look. As the rooms continued to convulse with furniture, a pattern emerged: although the pieces kept changing, their position stayed more or less the same. A bigger couch superseded a smaller one. A puffy chair with stubby legs supplanted a square one dressed in a box-pleated skirt. What's more, the arrangement of these new pieces duplicated that of our own furnishings. A new dining area appeared exactly where ours had been, with artfully mismatched antiques replacing our modern table and chairs.The team from Hollywood hadn't redesigned our house; they had merely switched out the objects and finishes. The sight lines, traffic patterns, and basic functions had stayed the same. Changing a slipcover to match the drapes isn't design in the most active sense.Design is thinking, materialized in objects and environments, inscribed in patterns of use, and addressed by analysis and planning. A work of design--be it a room, a jacket, or a page--results from deliberate thought. What is it for? What will it cost? How will it be used? Well-designed environments make sense, their beauty often resting in the transparency and accessibility of their functions. Design sometimes means exposing an environment's hidden agenda and making the most of it. If your dining room has become a place where books and papers are stacked, perhaps it's time to turn it into a library. If everyone in the house gravitates to the most comfortable chair, you may want to find other chairs like it. When people allow the functions of a room to ossify, they ignore the power of design.Do you control your environment, or does your environment control you? Moving the furniture is part of the philosophy of this book. The people in your world can become furniture, too, used but not noticed, made invisible through habit. Your calendar of routines and obligations is a floor plan for the day; make sure that each "room" is serving your needs and pleasures as best it can. At our house, moving the furniture has become a way of pulling happiness and sociability--in place of frustration and boredom--out of ordinary situations, simply by shaking them up a bit. EL 
Copyright © 2009 by Ellen Lupton and Julia Lupton. Paintings and illustrations copyright © 2009 by Ellen Lupton.

Most helpful customer reviews

5 of 6 people found the following review helpful.
"Design Your Life" is a wonderful book.
By Ian Blakeslee
"Design Your Life" is an excellent, entertaining read. It is funny, very clever, interesting, and useful. The wit is woven into humorous and critical examinations of the items and structure that is the context of our daily lives.

If you read this book, you will have a series of great "Aha!" moments as you gain a deeper understanding of how the design of your environment and the items you use influence and effect your behavior.

There is also a confortable amount of how-to and d.i.y. info to balance the humorous and historical.

As you read it you will feel your own ideas begin to spring forward. You will also think of people for whom it would be a perfect gift. Give it a try.

4 of 7 people found the following review helpful.
A real delight to have and to share
By Vivian Folkenflik
What a delight to share in the experience of having this brilliant, savvy, funny, practical, beautiful book in hand: an invitation to play,
construct, imagine, chat, reconfigure, connect. Both voices in this book
encourage us to open a conversation with them -- visually, verbally -- and with our multiple selves, with the people in our lives, with designers who
offer us opportunities to re-think the way we live now. A treat for
ourselves and for anybody we might want in our lives.

0 of 0 people found the following review helpful.
just the thing to dip into again and again for fun observations, clever writing
By Diana Glyer
A series of essays on design, beauty, pop culture, productivity, and the art of everyday life. A large format, glossy book, just the thing to dip into again and again for fun observations, clever writing, startling observations that elevate the ordinary. Recommended.

Diana Pavlac Glyer, author of BANDERSNATCH: C. S. Lewis, J. R. R. Tolkien, and the Creative Collaboration of the Inklings

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Sabtu, 18 Juni 2011

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Los alimentos /Medicina milagrosa (Spanish Edition), by Jean Carper

  • Sales Rank: #6787959 in Books
  • Published on: 2011-01-17
  • Original language: Spanish
  • Dimensions: 9.00" h x 6.50" w x 1.25" l,
  • Binding: Paperback
  • 480 pages

Most helpful customer reviews

0 of 0 people found the following review helpful.
Five Stars
By francisco panameno
This book is very good helps me know how to feed me to enjoy excellent health.

0 of 0 people found the following review helpful.
Four Stars
By Cesar Rosado
un libro muy interesante en cuanto a medicina no tradicional .

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The Dordogne takes you by surprise. Green and calm and quiet, at first glance it seems just another corner of rural France designed for good food, fine wine and easy living. Then you notice that it holds humanity's first great works of art, provocative paintings on the walls of its caves that go back over 15,000 years BC. It's been a busy crossroads ever since. The 'land of a thousand castles' has cinematic medieval donjons and turreted Renaissance châteaux to rival those of the Loire.  A dramatic history hasn't kept the Dordogne from polishing the arts of everyday life. There's an inviting cuisine based on duck, foie gras and truffles, and lovely villages of warm golden stone that complement some of France's most civilized landscapes.

  • Sales Rank: #1061419 in Books
  • Brand: Brand: Footprint Handbooks
  • Published on: 2010-09-01
  • Original language: English
  • Number of items: 1
  • Dimensions: .76" h x 6.16" w x 7.17" l, 1.17 pounds
  • Binding: Paperback
  • 288 pages
Features
  • Used Book in Good Condition

About the Author

Michael Pauls has lived in the Lot since 1989 and knows it like the back of his hand. With his wife Dana Facaros he has written over 30 books and frequently contributes to various publications in the UK. 

Most helpful customer reviews

8 of 8 people found the following review helpful.
Full Coverage
By Donald Cummings
This was pretty much the only book we used while traveling in the Perigord.
Frankly---it was MORE than enough. It covered the region splendidly.
Additionally, the writing style was very enjoyable...which we do enjoy in a travel book.
Nice pictures without being overdone.

Yes.

7 of 7 people found the following review helpful.
Dordogne one-book guide
By Constance
This guidebook has been very helpful in planning a trip to the Dordogne--history, accommodations, sites. The fine photographs help visualize the places. The print is a little small but this is a small quibble for an excellent guidebook. This is the only book you will need.

5 of 5 people found the following review helpful.
A very good guide
By Mike Donovan
Better than other guides to the region. Provides a general outlook for intending visitors to the Dordogne and Lot regions of France and enables planning of daily itineraries.

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Rabu, 08 Juni 2011

[N184.Ebook] Free Ebook The Best Damn Cisco Internetworking Book Period, by Charles Riley

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The Best Damn Cisco Internetworking Book Period shows readers everything they need to know about all Cisco internetworking topics. The book provides an understanding of Cisco's current VoIP solutions and the means to put them to work, showing how to configure all of Cisco's core VoIP products―among them Cisco CallManager software, Cisco 7910 series phones, and server-based IP PBXs. It discusses IPv6 Protocols, as well as IP Quality of Service (QoS) and how it applies to Enterprise and Internet Service Provider (ISP) environments.

In addition, Cisco wireless technologies are covered in detail. Cisco has placed a high priority on security and here readers will find complete coverage of all the Cisco Security products such as the PIX firewall suite of products, Network Address Translation (NAT), Cisco VPN Concentrator and IPSec, Cisco Authentication, Authorization, and Accounting (AAA), Content Services Switch (CSS), and the Cisco Secure Network Intrusion Detection System.

This book is sure to become a dog eared reference for all Cisco engineers and administrators.

- The one book that covers all major Cisco Internetworking concepts and configurations.
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- A 1-stop reference for Cisco professionals needing coverage of core Cisco exam topics.

  • Sales Rank: #3290161 in Books
  • Brand: Brand: Syngress
  • Published on: 2003-11-27
  • Format: Illustrated
  • Original language: English
  • Number of items: 1
  • Dimensions: 9.98" h x 2.06" w x 8.08" l, 4.90 pounds
  • Binding: Paperback
  • 800 pages
Features
  • Used Book in Good Condition

From the Publisher
This is the most comprehensive Cisco book available today. Any Cisco networking professional should have a copy and will find it an invaluable resource.

About the Author
Charles Riley (CCNP, CSS-1, CISSP, CCSA, MCSE, CNE-3) has co-authored several books including Routing and Configuring Cisco Voice over IP, Second Edition. Exhausting the educational offerings of Remington, Charles matriculated at the Model Secondary School for the Deaf in Washington, D.C.Quick to a decision and even quicker to change his mind, he moved to Florida where he graduated from the University of Central Florida in 1989. Upon graduation, Charles was contacted by and offered a position with the U.S. Army, a relationship that lasted over 10 years. As a consultant for Sprint, he designed and implemented robust networking solutions for large Fortune 500 and privately held companies.

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6 of 12 people found the following review helpful.
OK book, but not a sole source...
By A Customer
I found the book to contain too many errors, and the writing style was not user friendly (The book did not flow well). This book tries to cover many topics; some topics are covered very well, others fall far short. I do not recommend this book to anyone who is looking for solid reference guide. There are too many actual good books available out there.

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Selasa, 07 Juni 2011

[O989.Ebook] Ebook Download History of Violence, by John Wagner

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History of Violence, by John Wagner

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History of Violence, by John Wagner

'A History of Violence' is a stunning and uniquely cinematic tale of crime and retribution, soon to be a major movie from David Cronenberg.

  • Sales Rank: #17289632 in Books
  • Published on: 2011-10-01
  • Original language: English
  • Number of items: 1
  • Dimensions: 8.50" h x .63" w x 5.00" l, .0 pounds
  • Binding: Paperback
  • 296 pages

Review
"Mario Puzo collides with Norman Rockwell in a compelling tale of past crimes and present consequences" (Max Allan Collins (Road to Perdition))"

From the Publisher
It was just another quiet day at McKenna's Diner--until a couple of wanted killers walked in looking for trouble. Instead, they got bullets, and Tom McKenna got to be an instant media celebrity. That got him a lot of attention from some people he thought he'd escaped long ago. The kind of people who never forget a face--even after twenty years...

Now Tom must confront a group of cold-blooded mobsters intent on settling the score. As much as he tries to deny it, he's a man with a history of violence--and with the lives of his family hanging in the balance, he'll do anything to make sure his secret past stays buried...forever.END

About the Author
John Wagner is the award winning British writer (and co-creator) of Judge Dredd and has written the Star Wars series Dark Empire I & II Vincent Locke is an American comic book artist known for his work on Deadworld and A History of Violence and for his ultraviolent album covers for death metal band Cannibal Corpse.

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58 of 61 people found the following review helpful.
He can't run, he can't hide; but he CAN fight.
By Church of The Flaming Sword
Looking ever so forward to the David Cronenberg-directed adaptation of _A History of Violence_ to arrive at my local theater, I found it of the utmost exigency to buy the 1997 graphic novel that inspired it. And let me tell you, it does not disappoint one bit.

_AHoV_ tells of a small-town Michigan diner owner named Tom McKenna. McKenna is a nice guy with a loving wife, an adorable preschool daughter, and a quirky but still likable teenage son. Life is just one uneventful day after another - just as Tom likes it.

Until one day that should have been like every other, two thugs with robbery and murder on their minds enter Tom's diner for the first (and last) time. The hoodlums decide to push their luck until Tom is forced to kill one and badly injure the other. The press catches wind of the incident of course. While Tom is hailed as a hero by his friends and neighbors, he does whatever he can to downplay his newfound fame. It doesn't work.

Shortly after the failed robbery attempt, three mobsters from New York City come to the diner. All three of them have rap sheets with just about everything on them except broadcasting without the expressed written consent of Major League Baseball. Johnny Torrino, the leader of the three, is an aging assassin with failing eyesight looking for someone named "Joey", whom he needs to settle a score with. Torrino wears a necklace with a Joey's severed finger as a pendant. Mckenna, curiously enough, is missing one of his little fingers. Soon, it becomes evident that McKenna lived another life before settling down to small-town family life.

What makes _AHoV_ stand out from all the "edgy" graphic novels on the shelves is how it reads more like a great crime novel than just another graphic novel. It has a cinematic atmosphere that feels like what would happen if Martin Scorsese and Sam Peckinpah were to collaborate on a film. Make no mistake about it, this is one grisly read. Even with the borderline minimalist black and white artwork, the violence elicits more than a few cringes. Characters are either done in with or injured by bullets, axes, chainsaws, axes, power drills, etc. Take that "Suggested for Mature Readers" label seriously here.

But even with all the bloodshed, there is plenty of heart here as well. Tom and his family are presented as people just trying to keep their heads above water when faced with an unexpected and hostile situation. Tom does everything he believes he can do to keep his family of danger. You can't help but feel for the McKennas.

I love everything that _AHoV_ represents. There are no super"heroes" who are more attitude than personality, no superheroines who look like Playboy centerfolds, and no absurd comic book cliches. It's just a nice little (albeit graphically violent) tale of how the average American is anything but. For all those aspiring comics artists and writers trying to figure out how they are going to reinvent Superman the 16,549th time, read _AHoV_ and learn something new.

32 of 33 people found the following review helpful.
You Have a Gun in Your Face--What Do You Do?
By Ian Fowler
As other reviewers have noted, David Cronenberg's movie adaptation of "A History of Violence" will be released at the end of the year. This is the primary reason I picked up this graphic novel tha I passed on when it was first published. I'm glad I did pick it up, because John Wagner and Vincent Locke have crafted a gut-wrenching story of violence and revenge that transcends its lurid subject matter.

Wagner's premise is simple. Tom McKenna, husband and father of two, is closing up his diner when a couple of killers attempt to rob and murder him. Tom foils them, killing one in the process. Naturally, he receives a great deal of publicity, which he seeks to avoid. In short order, some very tough looking types come around looking a guy named Joey, a guy, it seems, who resembles Tom, right down to missing a finger. What follows is a hard-boiled tale in the best tradition of Ross MacDonald or Jim Thompson, as Tom finds his past catching up to him, and trying to eat him and his family alive, while Tom does everything in his power to beat that monster back (including killing a few people).

John Wagner is a British comic book writer, most remembered as a co-creator of Judge Dredd. That early work shows to some extent. "A History of Violence" is, well, violent, often appallingly so, as Tom is witness to, and himself inflicts, all manner of cruelty upon human beings. However, Wagner imbues his work with a soul. Tom and his wife, Edie, are good people, and Wagner makes it clear that whatever Tom has done, he has paid his dues. He deserves his happiness. That is underscored by the appalling antagonists Tom fights. Wagner further makes it plain that for Tom to win the final showdown, he still has to pay one last due.

Vince Locke's art is an interesting moody and sketchy style. It is highly detailed on the one hand, and yet his line work has an almost surreal quality, reminiscent of a woodcut. While it goes without saying the acts of violence are vivid (and almost difficult to view at times), Locke also depicts the more mundane aspects of the McKennas' lives, underscoring the everyman quality of Tom and the essentially average existence he leads.

Cronenberg has admitted in interviews that he did not know that the script for "A History of Violence" was originally a graphic novel until he and the screenwriter had gone through several drafts. Still, the advance reviews are good. The key to a successful translation of this GN to film is maintaining the central point: you have a gun in your face-what do you do?

17 of 20 people found the following review helpful.
I got this one after seeng the movie "based" on it - for Mature Readers only
By Kcorn
I'm glad I got the book, which is actually a very graphic comic book that goes far beyond the film version which is "based" on the book. This book is far superior to the film, in my view, although it is so graphic that I was wincing at parts of it. Imagine whatever weapon you want - chainsaws, drills, guns, knives...and you'll find them being used in this story. The drawings are very...detailed...and my tolerance wasn't as high as it should have been to handle all that blood and gore, at least not in illustrations. I prefer to read about stuff like that. Visuals can be too intense for me.

Still, don't let me scare you off. This book was not only believable but had integrity and heart, in its own violent, grisly way. I have to admit there were times I wished I was simply reading words on a page instead of having the images thrust in my face (this may also be the reason why the film sometimes seems "watered down" compared to the book, which is so graphic that it might have turned off film audiences).

You won't find any superheroes like Batman or Superman in this book. It is the type of comic that represents real life, starting with a guy, Tom, who seems to have a pretty low key life in a very small town. He runs the diner. He's barely on anyone's radar screen, apart from the people he knows in town and his wife and kids. He has a reputation for being a decent guy, even a better than average guy with a generous heart...but he's not particularly ambitious and he certainly isn't out to make waves. In fact, he PREFERS being out of the limelight - for reasons even his own family wouldn't suspect.

Everything changes when a couple of lowlifes come to town and try to rob him. He's forced to protect himself and those in the diner and he does so with amazing skill. Even so, no one suspects that this is particularly unusual, except for the fact that this type of crime doesn't usually happen in their town. So he's the hero of the local (and even the national) media for awhile and then it seems that things will die down.

Except that they dont...and in the process, Tom is forced to examine his entire life, going back to a childhood which wasn't always so peaceful, to hidden parts of his past...and he also puts his family in danger and tests his marriage and his wife's trust.

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